Identifying maximally informative signal-aware representations of single-cell data using the Information Bottleneck
Serafima Dubnov, Zoe Piran, Amit Alper, Adi Yefroimsky, Hermona Soreq, Mor Nitzan
The paper introduces bioIB, a framework using the Information Bottleneck method to extract compressed, signal-informative representations of scRNA-seq data, demonstrating its utility in diverse biological contexts.
Cell Systems · Apr 1, 2026Peer-reviewedBioinformatics