Hermona Soreq

This study identifies distinct blood small RNA profiles in panic disorder patients before and after internet-delivered cognitive behavioral therapy, linking specific microRNAs and tRFs to treatment response and immune pathways.

The paper profiles microRNA expression in human brain cell types to reveal cell-type specificity and age-related changes.

The paper introduces bioIB, a framework using the Information Bottleneck method to extract compressed, signal-informative representations of scRNA-seq data, demonstrating its utility in diverse biological contexts.

The paper shows maternal prenatal stress causes sex-dependent changes in tRNA fragments and cholinergic pathways in newborns.

This study shows that Klotho knockout affects brain microRNAs and tRNA fragments linked to aging and Alzheimer's disease in both mice and humans.

This study identifies RPL24 as a regulator of miR processing and tRF production, showing its interaction with DDX5 and its effect on miR levels and tRF profiles in human and plant cells.

This study identifies LysTTT-5tRF and miR-194-5p as co-regulators of hepatic steatosis through beta-Klotho and Perilipin 2, showing their cooperative roles in lipid metabolism.

The paper identifies inversely regulated immune-related genes linking anxiety and obesity in zebrafish, with differences observed between larvae and adults.

The paper identifies sex-specific changes in cholinergic-targeting tRNA fragments in Alzheimer's disease, linking them to cholinergic neuron loss and dementia.

The paper examines tRF levels in CSF and blood across age, sex, and Parkinson's disease, finding distinct patterns and suggesting their potential as biomarkers.

The paper identifies aging-associated differences in vesicle-bound and freely circulating small regulatory RNAs in mice, showing tRNA fragments and miRNAs strongly correlate with aging.

The paper develops a morphometric reconstruction pipeline to analyze cortical VIP/ChAT interneurons and finds insult-driven plasticity in their morphology and gene expression.

The paper develops an integrative transcriptomic approach to uncover sexually dimorphic microRNA regulation in schizophrenia and bipolar disorder, identifying disease-related pathways and potential biomarkers.