Cell BiologybioRxivPreprint
Human Pancreatic α-Cell Heterogeneity and Trajectory Inference Analysis Using Integrated Single Cell- and Single Nucleus-RNA Sequencing Platforms
Randy B. Kang, Jungeun Lee, Miguel Varela…·Geming Lu
This study identifies human α-cell and β-cell subtypes and trajectories using integrated scRNA-seq and snRNA-seq, revealing gene signatures for interconversion and highlighting in vivo transitions in T2D.