Author

Geming Lu

City Of Hope National Medical CenterORCID 0000-0002-1322-3997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adolfo Garcı́a-OcañaiD· 2 shared Peng WangiD· 2 shared Alberto PuglieseiD· 1 shared Andrew F. StewartiD· 1 shared Debbie C. ThurmondiD· 1 shared Eunjin OhiD· 1 shared FOUAD R. KANDEELiD· 1 shared Hung-Ping ShihiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Adolfo Garcı́a-OcañaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 22, 2026

Harmine Plus Exendin-4 Enhances Remission of Recent-Onset Type 1 Diabetes Following Anti-CD3 Therapy

Geming Lu, RANDY KANG, MIGUEL VARELA…·Adolfo Garcı́a-Ocaña

This study shows that harmine plus exendin-4, when combined with anti-CD3 therapy, promotes beta-cell recovery and reduces immunogenicity, leading to remission of recent-onset type 1 diabetes.

DOI 10.64898/2026.09.21.753317

mouseexperimental assay

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PhysiologyMolecular MetabolismPeer-reviewedJan 7, 2025

LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK

Joanna Filipowska, Zelda Cisneros, Sneha S. Varghese…·Rupangi C. Vasavada

This study shows LGR4 maintains beta-cell health by suppressing RANK, with effects observed in both in vitro and mouse models under stress and aging.

6 citations

mousehuman

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