Substrate stiffness and viscoelasticity influence fibroblast senescence
Mackenzie L. Skelton, Tanvi Bhat, Ethan Yu, Afia Ofori, Steven R. Caliari
This study shows that hydrogel stiffness and viscoelasticity influence fibroblast senescence, with viscoelasticity uniquely promoting senescence even without genotoxic stress.
Journal of Biomedical Materials Research Part A · Jun 23, 2026Peer-reviewedBioengineering