Conditional Myeloid-Specific Inhibition of UBE2N Hinders YUMM1.7 Growth
Kelsie Schiavone, Adam Pecoraro, Afsa Khawar, Kathleen Zhang, Daniel T. Starczynowski, Jennifer Y. Zhang
This study shows that inhibiting UBE2N in myeloid cells reduces YUMM1.7 melanoma growth by altering immune checkpoint molecules and SPP1 expression.
bioRxiv · Sep 1, 2026 · PreprintCancer Biology