Importance of taking Single Amino Acid Variant and accessory proteome variability into account in Data Independent Acquisition Proteomics: illustrated with Legionella pneumophila analysis
Agnès Dupas, Marine Ibranosyan, Christophe Ginévra, Sophie Jarraud, Jérôme Lemoine
The paper shows that incorporating allelic variability improves proteome coverage and identification confidence in DIA proteomics using Legionella pneumophila isolates.
bioRxiv · Apr 3, 2026 · PreprintBioinformatics