Marine Ibranosyan

Genetic diversity of Legionella species in culture-negative clinical and environmental specimens by sequencing the 23S-5S ribosomal intergenic spacer region

The paper develops a bioinformatic pipeline using 23S-5S rRNA sequencing to identify Legionella species in culture-negative PCR-positive samples, successfully assigning species in 60% of cases and revealing high diversity.

Importance of taking Single Amino Acid Variant and accessory proteome variability into account in Data Independent Acquisition Proteomics: illustrated with Legionella pneumophila analysis

The paper shows that incorporating allelic variability improves proteome coverage and identification confidence in DIA proteomics using Legionella pneumophila isolates.

Functional alterations of immune gene expression in ICU and non-ICU patients with Legionnaires' disease, a prospective observational study

This study compares immune gene expression in ICU and non-ICU Legionnaires' disease patients after LPS stimulation, finding more pronounced functional impairments in ICU patients.