Cancer BiologybioRxivPreprint
Transcriptomic Dichotomy in Melanoma: Proliferative Cell Cycle Shield vs. Autoimmune-like Chromatin Activation in Anti-PD-1 Response
Basma Shabana, Ahmed Salem, Nouraldeen Ali Ramadan, Ahmed Mahmoud Khedr
This study identifies two transcriptomic profiles in melanoma patients responding or not to anti-PD-1 therapy, linking resistance to a cell cycle shield and response to autoimmune-like chromatin activation.
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