Collective dynamics of DNA methylation during ageing
Aida M. Hashtroud, Marc Jan Bonder, Oliver Stegle, Ferdinand von Meyenn, Wolf Reik, Steffen Rulands
The paper shows that DNA methylation ageing is reflected in correlations between genomic loci, with a preference for 500 bp apart sites, and links this to PRC2-dependent H3K27me3 dilution.
bioRxiv · Dec 15, 2024 · PreprintGenomics