ASSET: A Framework for Decoding Aptamer Specificity of an Enriched Library by Next-Generation Sequencing of Experimental Samples
Maya N. Barros, Gayathri Kasirajan, Amara Jones, Aidan M Schlichting, Dario Ruiz-Ciancio, Li‐Hsien Lin, Chandan Narayan, Suresh Veeramani, Kristina W. Thiel, George Clare Kennedy, Isabel K. Darcy, William H. Thiel
ASSET quantifies aptamer specificity in enriched libraries using NGS, enabling accurate classification of true and false positives in SELEX processes.
bioRxiv · Aug 27, 2025 · PreprintMolecular Biology