Author

Isabel K. Darcy

University of IowaORCID 0000-0001-5068-1252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Aidan M Schlichting· 1 shared Amara Jones· 1 shared Chandan NarayaniD· 1 shared Dario Ruiz-CiancioiD· 1 shared Gayathri Kasirajan· 1 shared George Clare Kennedy· 1 shared Kristina W. ThieliD· 1 shared Li‐Hsien LiniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

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10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Aidan M Schlichting

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 27, 2025

ASSET: A Framework for Decoding Aptamer Specificity of an Enriched Library by Next-Generation Sequencing of Experimental Samples

Maya N. Barros, Gayathri Kasirajan, Amara Jones…·William H. Thiel

ASSET quantifies aptamer specificity in enriched libraries using NGS, enabling accurate classification of true and false positives in SELEX processes.

1 citation

statistical modelbenchmarking

𝕏 PostBluesky

Molecular BiologyBiology OpenPeer-reviewedJan 1, 2020

A topological analysis of difference topology experiments of condensin with Topoisomerases II

Soojeong Kim, Isabel K. Darcy

The paper simplifies difference topology experiments by using topoisomerases to trap DNA crossings and gel analysis to determine crossing numbers, applying this to model DNA topology bound by condensin and MukB.

DOI 10.1242/bio.048603

statistical model

𝕏 PostBluesky