Cdc48 and its co-factor Ufd1 segregate CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe.
Yukiko Nakase, Hiroaki Murakami, Michiko Suma, Kaho Nagano, Airi Wakuda, Teppei Kitagawa, Tomohiro Matsumoto
This paper shows that Cdc48 and Ufd1 remove excess CENP-A from chromatin in fission yeast, maintaining proper centromere function and preventing chromosome missegregation.
bioRxiv · Jun 15, 2023 · PreprintMolecular Biology