A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator of HIV latency
Samuel D. Burgos, Airlie Ward, Manickam Ashokkumar, Kimberly P. Enders, Lindsey Ingerman James, David M. Margolis, Edward P. Browne
The paper identifies TAF1 as a novel regulator of HIV latency through a chemical screen and genetic experiments, showing its role in maintaining viral transcriptional silence.
mBio · Jun 15, 2026Peer-reviewedMicrobiology