Shared genetic architecture between brain iron deposition and Alzheimer's disease
Md Rezanur Rahman, Ying Xia, Parnesh Raniga, Amir Fazlollahi, Tania Islam, Aishwarya Dhruva, Jue‐Sheng Ong, Stuart MacGregor, Ashley I. Bush, Jürgen Fripp, Michelle K. Lupton
This study identifies shared genetic factors between brain iron deposition and Alzheimer's disease, revealing a polygenic basis and potential neuroimmune mechanisms.
medRxiv · Sep 9, 2026 · PreprintGenetic & Genomic Medicine