Morphomechanically-Informed Spatial Curvature Sequencing in Prostate Cancer
Ivan Kordic, Felix G. Rivera Moctezuma, Hoseyn A. Amiri, Ajie Liu, Shuangyi Cai, Mehdia Nadeem Rajab Ali, Lourdes T. Brea, Abhijeet Venkataraman, Hongshun Shi, Lara Rabih Harik, Todd Sulchek, Jindan Yu, Ahmet F. Coskun
This paper introduces CurvSeq and CurvSee to analyze prostate cancer morphology and molecular profiles, identifying cancer-associated genes and morphomechanical niches linked to progression.
bioRxiv · Jul 23, 2026 · PreprintSystems Biology