Mitochondrial Dysfunction and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
Kazuaki Mori, Akinobu Togo, Kota Yamashita, Shigeo Sakuragi, Hiroko Bannai, Taishi Umezawa, Keisuke Ohta, Toru Asahi, Chihiro Nozaki, Kosuke Kataoka
This study shows that CB1R antagonists induce apoptosis in SH-SY5Y cells under serum-free conditions through mitochondrial dysfunction and ER stress.
Neuropharmacology · Oct 24, 2024Peer-reviewedPharmacology & Toxicology