Author

Akito Shikama

University of Tsukuba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Naoya YahagiiD· 2 shared Rika Saikawa· 2 shared Samia Karkoutly· 2 shared Tsolmon Mendsaikhan· 2 shared Yoshinori TakeuchiiD· 2 shared Yuichi Aita· 2 shared Yukari Masuda· 2 shared Yuki MurayamaiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Naoya YahagiORCID

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2 papers

Recent·Most cited

KLF15 regulates sulfur amino acid metabolism through Cystathionine gamma-lyase

Zahra Mehrazad Saber, Yoshinori Takeuchi, Samia Karkoutly, Masato Higaki, Tsolmon Mendsaikhan, Rika Saikawa, Yuichi Aita, Yuki Murayama, Akito Shikama, Yukari Masuda, Naoya Yahagi

This study identifies KLF15 as a regulator of CTH, showing it enhances hepatic sulfur amino acid metabolism through H2S and taurine production during high-protein diets.

bioRxiv · Aug 31, 2026 · PreprintBiochemistry

FoxO transcription factors couple the urea cycle and gluconeogenesis by controlling Ass1

Samia Karkoutly, Yoshinori Takeuchi, Zahra Mehrazad Saber, Duhan Tao, Tsolmon Mendsaikhan, Rika Saikawa, Yuichi Aita, Yuki Murayama, Akito Shikama, Yukari Masuda, Naoya Yahagi

This study identifies FoxO transcription factors as regulators of Ass1, linking urea cycle and gluconeogenesis during fasting.

bioRxiv · Dec 23, 2025 · PreprintBiochemistry