Author

Yuichi Aita

University of Tsukuba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

Naoya YahagiiD· 3 shared Yoshinori TakeuchiiD· 3 shared Yuki MurayamaiD· 3 shared Akito Shikama· 2 shared Rika Saikawa· 2 shared Samia Karkoutly· 2 shared Tsolmon Mendsaikhan· 2 shared Yukari Masuda· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

Naoya YahagiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

KLF15 regulates sulfur amino acid metabolism through Cystathionine gamma-lyase

Zahra Mehrazad Saber, Yoshinori Takeuchi, Samia Karkoutly, Masato Higaki, Tsolmon Mendsaikhan, Rika Saikawa, Yuichi Aita, Yuki Murayama, Akito Shikama, Yukari Masuda, Naoya Yahagi

This study identifies KLF15 as a regulator of CTH, showing it enhances hepatic sulfur amino acid metabolism through H2S and taurine production during high-protein diets.

bioRxiv · Aug 31, 2026 · PreprintBiochemistry

FoxO transcription factors couple the urea cycle and gluconeogenesis by controlling Ass1

Samia Karkoutly, Yoshinori Takeuchi, Zahra Mehrazad Saber, Duhan Tao, Tsolmon Mendsaikhan, Rika Saikawa, Yuichi Aita, Yuki Murayama, Akito Shikama, Yukari Masuda, Naoya Yahagi

This study identifies FoxO transcription factors as regulators of Ass1, linking urea cycle and gluconeogenesis during fasting.

bioRxiv · Dec 23, 2025 · PreprintBiochemistry

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at ER monitoring and regulating fatty acids

Song‐iee Han, Masanori Nakakuki, Yoshimi Nakagawa, Yunong Wang, Masaya Araki, Yuta Yamamoto, Hiroaki Tokiwa, Hiroyuki Takeda, Yuhei Mizunoe, Kaori Motomura, Hiroshi Ohno, Yuki Murayama, Yuichi Aita, Yoshinori Takeuchi, Yoshinori Osaki, , Hitoshi Shimano

The paper shows RHBDL4 cleaves SREBP-1c at the ER, with its activity modulated by fatty acid types, and demonstrates its role in lipid homeostasis.

bioRxiv · Aug 24, 2021 · PreprintMolecular Biology