Attenuating the DNA damage response to double strand breaks is neuroprotective
Richard I. Tuxworth, Matthew J. Taylor, Ane Martín Anduaga, Alaa Hussien-Ali, Sotiroula Chatzimatthaiou, Joanne Longland, Adam M. Thompson, Sharif Almutiri, Pavlos Alifragis, Charalambos Panayiotis Kyriacou, Boris P. Kysela, Zubair Ahmed
The paper shows that reducing the DNA damage response in neurons protects against neurodegeneration and promotes regeneration in multiple models.
Brain Communications · Jan 1, 2019Peer-reviewedNeuroscience