Multi-resolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism
Anthony Yan-Tang Wu, Yun-Chieh Sung, Yen-Ju Chen, Steven Ting-Yu Chou, Vanessa Guo, Jasper Che-Yung Chien, John Jun-Sheng Ko, Alan Ling Yang, Hsi-Chien Huang, Ju-Chen Chuang, Ysuan Wu, Meng-Ru Ho, Maria Ericsson, Wan-Wan Lin, Chantal Hoi Yin Cheung, , Charles Pin-Kuang Lai
The paper develops a BRET-based reporter to track extracellular particles in vivo, revealing distinct biodistribution profiles and tropism of HCC-derived EPs.
bioRxiv · Mar 27, 2020Cell Biology