Maternal genetic variants in kinesin motor domains prematurely increase egg aneuploidy
Leelabati Biswas, Katarzyna M. Tyc, Mansour Aboelenain, Siqi Sun, Iva Dundović, Kruno Vukušić, Jason Liu, Vanessa Guo, Min Xu, Richard T. W. Scott, Xin Tao, Iva M. Tolić, Jinchuan Xing, Karen Schindler
The study identifies genetic determinants of reproductive aging linked to egg aneuploidy by analyzing maternal exomes and shows kinesin gene variants contribute to aneuploidy and accelerated aging.
Proceedings of the National Academy of Sciences · Oct 30, 2024Peer-reviewedGenetic & Genomic Medicine