Definitive Hematopoietic Stem Cells Minimally Contribute to Embryonic Hematopoiesis
Bianca A. Ulloa, Samima Sultana Habbsa, Kathryn S. Potts, Alana Lewis, Mia McKinstry, Sara G. Payne, Julio C. Flores, Anastasia Nizhnik, María Feliz Norberto, Christian Mosimann, Teresa Venezia Bowman
This study shows nascent hematopoietic stem cells (HSCs) self-renew but have delayed differentiation during embryonic hematopoiesis, with HSC-independent progenitors driving early blood development.
Cell Reports · Sep 1, 2021Peer-reviewedDevelopmental Biology