Teresa Venezia Bowman

This study shows that CT-179, an OLIG2 inhibitor, reduces glioblastoma growth and enhances chemoradiotherapy efficacy in preclinical models.

This study shows that inhibiting TGF-β signaling during embryonic hematopoiesis alters HSPC behavior and leads to long-term changes in immune function and clonal diversity.

This study uses spatial and single-cell transcriptomics to identify immune-stromal niches in adult-onset dermatomyositis, revealing distinct cellular and cytokine signatures associated with cancer and non-cancer lesions.

This study uses spatial transcriptomics to identify CD8+ T cell-driven mechanisms of kidney damage in ICI-AIN, showing increased IFN-γ signaling and proinflammatory myeloid cell activation.

The paper uses zebrafish developmental lineage tracing and single-cell RNA sequencing to show that early HSPCs favor lymphoid lineage while later HSPCs skew towards erythroid, with early HSPCs contributing to adult lymphocytes.

The paper identifies abundant RNA-binding proteins in mouse lenses and characterizes their interactions with crystallin and β-actin mRNAs using proteomic, transcriptomic, and imaging techniques.

The paper identifies Khdrbs1 as critical for hematopoietic stem and progenitor cell emergence via splicing regulation in zebrafish.

This study shows nascent hematopoietic stem cells (HSCs) self-renew but have delayed differentiation during embryonic hematopoiesis, with HSC-independent progenitors driving early blood development.

This study shows that pericentromeric hypomethylation in zebrafish triggers an interferon response, linking it to ICF syndrome-like phenotypes.