Cognitive impairment and metabolite profile alterations in the hippocampus and cortex of male and female mice exposed to a fat and sugar-rich diet are normalized by diet reversal
Alba M Garcia-Serrano, Adélaïde A. Mohr, Juliette Philippe, Cecilia Skoug, Peter Spégel, João M. N. Duarte
This study shows that a high-fat and high-sucrose diet causes reversible metabolic and behavioral changes in mice, which normalize upon diet reversal.
Aging and Disease · Jan 1, 2022Peer-reviewedNeuroscience