João M. N. Duarte

This paper develops a harmonized MRI QC framework using phantoms to identify sources of variability across field strengths and sites, showing that field strength alone does not fully characterize MRI performance.

This study uses 7T 31P fMRS to show NAD+ decreases during visual stimulation in the human occipital lobe, with no change in other metabolites.

This study examines sex-specific hypothalamic inflammation in mice fed a high-fat and high-sucrose diet and finds partial recovery after diet normalization.

This study shows that palmitate exposure causes microglia to change their metabolism and release EVs that affect behavior and metabolism in mice.

This study shows that taurine and N-acetylcysteine prevent memory impairment and hippocampal metabolite changes in high-fat diet-fed female mice, with NAC also restoring energy metabolism.

This study shows that a high-fat and high-sucrose diet causes reversible metabolic and behavioral changes in mice, which normalize upon diet reversal.

This study shows that HSL is present in synapses and its deletion in mice impairs memory but not exploratory behavior, with changes in lipid profiles and inflammation.