Comprehensive investigation of AAV tropism across human iPSC-derived neuronal subtypes
Linus Wiora, Salvador Rodrı́guez-Nieto, Leelja Rößler, Jacob Helm, Alejandra Leyva, Thomas Gasser, Ludger J. Schöls, Ashutosh Dhingra, Stefan Hauser
This study evaluates AAV transduction efficiency and toxicity across human iPSC-derived neuronal subtypes, identifying optimal serotypes for gene delivery in vitro.
bioRxiv · Mar 30, 2026 · PreprintNeuroscience