Author

Alejandro J. Gupta

Koch Institute for Integrative Cancer Research At MIT

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan DenAdeliD· 1 shared Alex K. ShalekiD· 1 shared Alexandria Van ScoykiD· 1 shared Andrew W. NaviaiD· 1 shared Ava P. AminiiD· 1 shared Catharine S. Leahy· 1 shared Charles CouturieriD· 1 shared David M. WeinstockiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alan DenAdelORCID

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1 paper

Recent·Most cited

Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease

Peter S. Winter, Michelle L. Ramseier, Andrew W. Navia, Sachit D. Saksena, Haley Strouf, Nezha Senhaji, Alan DenAdel, Mahnoor Mirza, Hyun Hwan An, Laura L. Bilal, Peter S. Dennis, Catharine S. Leahy, Kay Shigemori, Jennyfer Galvez-Reyes, Ye Zhang, , Mark Alan Murakami

This study identifies mutation and transcriptional state compatibility in Ph+ ALL MRD, showing that targeting these interactions can overcome BCR::ABL1 independence and improve MRD monitoring.

bioRxiv · Jun 6, 2024 · PreprintCancer Biology