Investigating the structural effects of anti-thrombin anticoagulant aptamers on activation of human prothrombin
Romualdo Troisi, Alessandro Cangiano, Nathan Philip Cowieson, Vera A. Spiridonova, Nicola Pozzi, Pompea Del Vecchio, Luigi Paduano, Filomena Sica
This study investigates how anti-thrombin aptamers affect prothrombin activation by analyzing their structural interactions and binding effects.
Molecular Therapy · Jul 24, 2026Peer-reviewedBiophysics