Author

Alessio Ostini

University of Bern

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Biology Disciplines

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Physiology· 1

Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1

Frequent Co-Authors

André G. KléberiD· 1 shared Jan KučeraiD· 1 shared Jeffrey E. SaffitziD· 1 shared Yoram RudyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperPhysiology

André G. KléberORCID

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1 paper

Recent·Most cited

Computational Modeling of Effects of PKP2 Gene Therapy on Ventricular Conduction Properties in Arrhythmogenic Cardiomyopathy

Alessio Ostini, André G. Kléber, Yoram Rudy, Jeffrey E. Saffitz, Jan Kučera

This study uses computational models to show that low levels of PKP2 gene therapy transduction in ACM patients do not significantly improve conduction velocity but may increase conduction block risk with higher transduction.

Circulation Arrhythmia and Electrophysiology · Apr 9, 2025Peer-reviewedPhysiology