Author

Alex Bridgland

Google DeepMind (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:protein sequence· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alexander PritzeliD· 2 shared Andrew CowieiD· 2 shared Andrew SenioriD· 2 shared Anna PotapenkoiD· 2 shared Augustin ŽídekiD· 2 shared Demis HassabisiD· 2 shared Ellen ClancyiD· 2 shared John JumperiD· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Alexander PritzelORCID

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Author profile →

2 papers

Recent·Most cited

Protein complex prediction with AlphaFold-Multimer

Richard Evans, Michael O’Neill, Alexander Pritzel, Natasha Antropova, Andrew Senior, Tim Green, Augustin Žídek, Russ Bates, Sam Blackwell, Jason Yim, Olaf Ronneberger, Sebastian W. Bodenstein, Michal Zielinski, Alex Bridgland, Anna Potapenko, , Demis Hassabis

AlphaFold trained on complexes, with cross-chain paired alignments and symmetry-aware losses, gets 70% of recent heteromeric interfaces acceptable or better (DockQ ≥ 0.23), 27 points above linker-joined AlphaFold.

bioRxiv · Oct 4, 2021 · PreprintBioinformatics✦ In-depth digest

Highly accurate protein structure prediction with AlphaFold

John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon Köhl, Andrew J. Ballard, Andrew Cowie, , Demis Hassabis

AlphaFold, an attention network over sequence alignments and residue pairs, rivaled experimental accuracy in most CASP14 cases: median backbone r.m.s.d.95 0.96 Å versus 2.8 Å for the runner-up.

Nature · Jul 15, 2021Peer-reviewedBiophysics✦ In-depth digest