Author

Andrew Cowie

Google DeepMind (United Kingdom)ORCID 0000-0002-4491-1434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:protein sequence· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alex Bridgland· 2 shared Alexander PritzeliD· 2 shared Andrew SenioriD· 2 shared Anna PotapenkoiD· 2 shared Augustin ŽídekiD· 2 shared Demis HassabisiD· 2 shared Ellen ClancyiD· 2 shared John JumperiD· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Alex Bridgland

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 4, 2021

✦ In-depth digest

Protein complex prediction with AlphaFold-Multimer

Richard Evans, Michael O’Neill, Alexander Pritzel…·Demis Hassabis

AlphaFold trained on complexes, with cross-chain paired alignments and symmetry-aware losses, gets 70% of recent heteromeric interfaces acceptable or better (DockQ ≥ 0.23), 27 points above linker-joined AlphaFold.

3,798 citations

protein structureprotein sequence

𝕏 PostBluesky

BiophysicsNaturePeer-reviewedJul 15, 2021

✦ In-depth digest

Highly accurate protein structure prediction with AlphaFold

John Jumper, Richard Evans, Alexander Pritzel…·Demis Hassabis

AlphaFold, an attention network over sequence alignments and residue pairs, rivaled experimental accuracy in most CASP14 cases: median backbone r.m.s.d.95 0.96 Å versus 2.8 Å for the runner-up.

43,764 citationstop 1%

multiple speciesprotein structure

𝕏 PostBluesky