Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete.
Douglas Sweeney, Alexander Bogdanov, Alexander B. Chase, Gabriel Castro‐Falcón, Alma Trinidad-Javier, Samira Dahesh, Victor Nizet, Paul R. Jensen
The paper uses pattern-based genome mining to discover indanopyrrole A, a novel antibiotic from a marine Streptomyces, and links it to an orphan biosynthetic gene cluster.
Journal of Natural Products · Nov 22, 2024Peer-reviewedBiochemistry