USP11 deubiquitinates monoubiquitinated SPRTN to repair DNA-protein crosslinks
Megan C. Perry, Sai Sundeep Kollala, Meghan Biegert, Grace Su, Manohar M. Kodavati, Halle J. Mallard, Natasha F. Kreiling, Alexander Holbrook, Gargi Ghosal
This study identifies USP11 as a deubiquitinase that regulates SPRTN function in DNA-protein crosslink repair by removing monoubiquitin from SPRTN.
bioRxiv · Jun 30, 2020 · PreprintMolecular Biology