Author
Fred and Pamela Buffett Cancer CenterORCID 0000-0001-8399-5354Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Borum Ryu, Thomas C. Caffrey, Sriya Sridhar…·Grinu Mathew
This paper establishes patient-derived models of neuroendocrine prostate cancer (NEPC) from metastases, showing they retain tumor heterogeneity and can model metastatic progression.
Niphat Jirapongwattana, Carley M. Conover, Catalina Trujillo Jaramillo…·Adam R. Karpf
This study identifies a RHNO1-ATR/Chk1 positive feedback loop that sustains DNA replication stress response and highlights RHNO1 as a therapeutic target in cancer.
Kirk L. West, Tram T N Nguyen, Kyle Tengler…·Justin W. C. Leung
This study shows that TLK1 and TLK2 hyper-autophosphorylation suppresses their recruitment to damaged chromatin by masking the PIP-box, which is required for PCNA interaction.
Megan C. Perry, Sai Sundeep Kollala, Meghan Biegert…·Gargi Ghosal
This study identifies USP11 as a deubiquitinase that regulates SPRTN function in DNA-protein crosslink repair by removing monoubiquitin from SPRTN.