A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy
Bingxue Qi, Vishal Musale, Xiong Weng, Ayman K. Banah, Alexander Lawlor, Colin E. Murdoch, Abigail C. Lay, Kate J. Heesom, Richard J.M. Coward, Christopher Lund O'Connor, Wenjun Ju, Markus Bitzer, Claire Elizabeth Hills, Yang Chen, Li Kang
This study identifies HA and its receptors CD44/RHAMM as key drivers of obesity-related glomerulopathy, showing their role in renal inflammation, fibrosis, and dysfunction, and suggests they as therapeutic targets.
Biomolecules · Nov 14, 2025Peer-reviewedPhysiology