Malaria-induced remodelling of the bone marrow microenvironment mediates loss of haematopoietic stem cell function
Myriam L.R. Haltalli, Samuel Watcham, Nicola K. Wilson, Kira Eilers, Alexander Lipien, Maria L. Vainieri, Nicola Ruivo, Heather Ang, Robert E. Sinden, Ken R. Duffy, Berthold Göttgens, Andrew M. Blagborough, Cristina Lo Celso
This study investigates how malaria infection alters the bone marrow microenvironment, leading to impaired haematopoietic stem cell function through changes in endothelium and osteoblasts.
bioRxiv · Nov 22, 2018 · PreprintCell Biology