IFNβ and TNFα cooperate to induce a STAT1-independent antiviral and immunoregulatory program via non-canonical STAT2 and IRF9 pathway
Mélissa K. Mariani, Pouria Dasmeh, Audray Fortin, Elise Caron, Mario Kalamujic, Alexander N. Harrison, Dacquin M. Kasumba, Sandra Cervantes-Ortiz, Espérance Mukawera, Adrian W.R. Serohijos, Nathalie Grandvaux
The paper shows that IFNβ and TNFα together induce a STAT1-independent antiviral program via non-canonical STAT2 and IRF9 pathways.
bioRxiv · Nov 7, 2018 · PreprintImmunology