Nathalie Grandvaux

The paper develops a stable reporter cell line to quantify NS2-mediated inhibition of IFNB promoter activation in RSV infection.

This study shows that the multivalent prefusion SARS-CoV-2 Spike protein does not directly activate human neutrophils ex vivo, even in the presence of anti-S antibodies.

This study identifies host proteins incorporated into HCoV-OC43 virions and virus-modulated extracellular vesicles, revealing their roles in viral spread and extracellular vesicle composition.

The paper introduces AlphaFold-pairs, a computational method to predict protein-protein interactions, validated on human and viral systems, revealing new interactions in SARS-CoV-2 and Influenza A virus.

The paper identifies TRAF6 as an interactor of misfolded SOD1 in ALS, showing it promotes aggregation through ubiquitination.

The paper shows that IFNβ and TNFα together induce a STAT1-independent antiviral program via non-canonical STAT2 and IRF9 pathways.