Author

Alexander S. Cruz

The Jackson Laboratory for Genomic Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Brandon SaavedraiD· 1 shared Cornelis BlauwendraatiD· 1 shared Gang NingiD· 1 shared Justin A. McDonoughiD· 1 shared Kevin HoldeniD· 1 shared Mark R. CooksoniD· 1 shared Michael Emmerson WardiD· 1 shared Sofia Giansiracusa· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Brandon SaavedraORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintDec 16, 2021

Controlling homology-directed repair outcomes in human stem cells with dCas9

William C. Skarnes, Gang Ning, Sofia Giansiracusa…·Justin A. McDonough

This paper improves Cas9 RNP editing in human stem cells to achieve high rates of biallelic homology-directed repair of SNVs by using dCas9 to block re-cutting and damage.

11 citations

humanCRISPR screen

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