Author

Brandon Saavedra

Stanford MedicineORCID 0000-0003-4211-9993Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam C. WilkinsoniD· 1 shared Alexander S. Cruz· 1 shared Cornelis BlauwendraatiD· 1 shared Gang NingiD· 1 shared Haojun XuiD· 1 shared Hiromitsu NakauchiiD· 1 shared Jonas L. FowleriD· 1 shared Jonathan VillanuevaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Adam C. WilkinsonORCID

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2 papers

Recent·Most cited

ImmunologyMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedJun 18, 2025

Development of iPSC-Derived T Cells Targeting EGFR Neoantigens in Non-Small Cell Lung Cancer

Kouta Niizuma, Toshinobu Nishimura, Jonathan Villanueva…·Hiromitsu Nakauchi

This study develops iPSC-derived T cells targeting the EGFR C797S mutation in NSCLC, showing their ability to recognize and kill cancer cells expressing this mutation.

3 citations

humanexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 16, 2021

Controlling homology-directed repair outcomes in human stem cells with dCas9

William C. Skarnes, Gang Ning, Sofia Giansiracusa…·Justin A. McDonough

This paper improves Cas9 RNP editing in human stem cells to achieve high rates of biallelic homology-directed repair of SNVs by using dCas9 to block re-cutting and damage.

11 citations

humanCRISPR screen

𝕏 PostBluesky