Intrinsic Heterogeneity of Primary Cilia Revealed Through Spatial Proteomics
Jan N. Hansen, Huangqingbo Sun, Konstantin Kahnert, Eini Westenius, Alexandra Johannesson, Carmela Villegas, Trang H. Le, Kalliopi Tzavlaki, Casper F. Winsnes, Emmie Pohjanen, Anna Mäkiniemi, Jenny Fall, Frederic Ballllosera Navarro, Anna Bäckström, Cecilia Lindskog, , Emma K. Lundberg
The paper uses spatial proteomics to analyze primary cilia proteomes across cell lines, revealing cell-type specificity and single-cilia heterogeneity, and identifies novel cilia proteins and potential genetic variants.
Cell · Sep 26, 2025Peer-reviewedCell Biology