Author

Alexandra Reinbrecht

University Medical Center of the Johannes Gutenberg University Mainz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Edite Antunes Ferreira· 1 shared Hakim EchchannaouiiD· 1 shared Kevin Jan Legscha· 1 shared Matthias TheobaldiD· 1 shared Ulrike Regina Schmits· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Edite Antunes Ferreira

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1 paper

Recent·Most cited

A signaling-optimized TIGIT chimeric switch receptor promotes metabolic fitness and antitumor efficacy of TCR/CAR T cells

Edite Antunes Ferreira, Kevin Jan Legscha, Ulrike Regina Schmits, Alexandra Reinbrecht, Matthias Theobald, Hakim Echchannaoui

This paper introduces a fine-tuned chimeric switch receptor (CSR) that enhances TCR/CAR T cell metabolic fitness and antitumor efficacy by optimizing signaling from the TIGIT domain.

bioRxiv · Oct 8, 2026 · PreprintImmunology