Understanding the kinetics of macrophage uptake and the metabolic fate of iron-carbohydrate complexes used for iron deficiency anemia treatment
Stephanie Eitner, Vera Maria Kissling, Alexandra Rippl, Leonard Krupnik, J.J. Burgi, Stefanie Gächter, Katharina Hast-Sribike, Alexander Gogos, Davide Bottone, Jonas Bossart, Rafael Riudavets Puig, Reinaldo G. Digigow, Amy E. Barton Alston, Beat Flühmann, Peter Wick, Vanesa Ayala‐Nunez
This study investigates the uptake and metabolic fate of two iron-carbohydrate complexes in macrophages, revealing distinct intracellular behaviors that affect their therapeutic outcomes.
Journal of Controlled Release · Sep 5, 2025Peer-reviewedPharmacology & Toxicology