Author

Davide Bottone

EmpaORCID 0000-0002-6133-5088Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander GogosiD· 2 shared Vera Maria KisslingiD· 2 shared Alexandra Rippl· 1 shared Amy E. Barton Alston· 1 shared Beat FlühmanniD· 1 shared Inge Katrin HerrmanniD· 1 shared J.J. BurgiiD· 1 shared Johannes RiemanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Alexander GogosORCID

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2 papers

Recent·Most cited

BioinformaticsSmallPeer-reviewedOct 27, 2026

3D Reconstruction of Nanoparticle Distribution in Tumor Spheroids with Volume Electron Microscopy

Davide Bottone, Lukas R. H. Gerken, Sebastian F. M. Habermann…·Inge Katrin Herrmann

The paper presents an end-to-end pipeline for segmenting nanoparticles and cellular structures in 3D electron microscopy data of tumor spheroids, revealing preferential NP clustering near nuclei.

DOI 10.1002/smll.75947

electronic health recordsstatistical model

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Pharmacology & ToxicologyJournal of Controlled ReleasePeer-reviewedSep 5, 2025

Understanding the kinetics of macrophage uptake and the metabolic fate of iron-carbohydrate complexes used for iron deficiency anemia treatment

Stephanie Eitner, Vera Maria Kissling, Alexandra Rippl…·Vanesa Ayala‐Nunez

This study investigates the uptake and metabolic fate of two iron-carbohydrate complexes in macrophages, revealing distinct intracellular behaviors that affect their therapeutic outcomes.

8 citationstop 3%

humanbulk RNA-seq

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