How informative are structural alphabets for representing protein folds?
Ferras El-Hendi, Ali H. Al-Fatlawi, Md. Ballal Hossen, Tom Kasper, Alexandre Mestiashvili, Michael Schroeder
This study evaluates how well three structural alphabets retain fold-level information compared to full-structure comparisons using TM-scores as a reference.
bioRxiv · Sep 29, 2026 · PreprintBioinformatics