Author

Ferras El-Hendi

Center for Scalable Data Analytics and Artificial IntelligenceORCID 0009-0004-5784-5482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Assay:protein sequence· 1

Frequent Co-Authors

Michael SchroederiD· 3 shared Ali H. Al-FatlawiiD· 2 shared Md. Ballal Hossen· 2 shared Alexandre Mestiashvili· 1 shared Lukas Buschmann· 1 shared Negin Malekian· 1 shared Sarah Naomi BolziD· 1 shared Tom Kasper· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersBioinformatics

Michael SchroederORCID

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3 papers

Recent·Most cited

How informative are structural alphabets for representing protein folds?

Ferras El-Hendi, Ali H. Al-Fatlawi, Md. Ballal Hossen, Tom Kasper, Alexandre Mestiashvili, Michael Schroeder

This study evaluates how well three structural alphabets retain fold-level information compared to full-structure comparisons using TM-scores as a reference.

bioRxiv · Sep 29, 2026 · PreprintBioinformatics

Much ado about nothing: Modelling amino acid replacement with predicted protein structures

Lukas Buschmann, Sarah Naomi Bolz, Ferras El-Hendi, Negin Malekian, Michael Schroeder

The paper benchmarks a new substitution matrix derived from AlphaFold-predicted structures against existing matrices, finding similar performance and highlighting the diminishing role of substitution matrices with more sequence data.

Bioinformatics · Apr 24, 2026Peer-reviewedBioinformatics

Protein secondary structure and remote homology detection

Ali H. Al-Fatlawi, Md. Ballal Hossen, Ferras El-Hendi, Michael Schroeder

The paper evaluates secondary structure's effectiveness in remote homology detection and finds a simple string comparison on secondary structure performs nearly as well as tertiary structure alignment.

bioRxiv · Sep 3, 2024 · PreprintBioinformatics