PathologybioRxivPreprint
Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype
Alberto Malerba, Fanny Roth, Pradeep Harish…·Capucine Trollet
This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.
DOI 10.1101/375758