Author

Alexey A. Sergushichev

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Biology Disciplines

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Genomics· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

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Alexander V. Predeus· 1 shared Maxim N. Artyomov· 1 shared Pavel N. Zakharov· 1 shared

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2015-2015 · peak 1/yr

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1 shared paperGenomics

Alexander V. Predeus

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJan 15, 2015

Model based normalization improves differential expression calling in low-depth RNA-seq

Pavel N. Zakharov, Alexey A. Sergushichev, Alexander V. Predeus, Maxim N. Artyomov

The paper introduces a normalization method that improves differential expression analysis at low sequencing depths by re-normalizing samples using a Pareto-like distribution model.

DOI 10.1101/013854

bulk RNA-seqstatistical model

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