Genetic compensation in podocalyxin-like mutants during zebrafish liver development
Alexis N. Ross, Natalie M Miscik, Sharanya Maanasi Kalasekar, James D Harris, Lisa Tran, Aavrati Saxena, Steven Andrew Baker, Kimberley Jane Evason
This study investigates the role of podxl in zebrafish liver development and finds that its loss leads to reduced HSC numbers, with compensation through upregulation of extracellular matrix genes.
bioRxiv · Apr 7, 2025 · PreprintDevelopmental Biology